The molecules adopt near-perfect tetrahedral symmetry with average Sn–Cl distances of 227.9(3) pm.

[1] Anhydrous tin(IV) chloride is a major precursor in organotin chemistry.

Upon treatment with Grignard reagents, tin(IV) chloride gives tetraalkyltin compounds:[5] Anhydrous tin(IV) chloride reacts with tetraorganotin compounds in redistribution reactions: These organotin halides are useful precursors to catalysts (e.g., dibutyltin dilaurate) and polymer stabilizers.

[1] For example, the acetylation of thiophene to give 2-acetylthiophene is promoted by tin(IV) chloride.

[8] Stannic chloride was used as a chemical weapon in World War I, as it formed an irritating (but non-deadly) dense smoke on contact with air.