Titusville /ˈtɪtəsvəl/ is a historic neighborhood in Birmingham, Alabama, United States southeast of Ensley near UAB's campus.

Since the early twentieth century Titusville has been a neighborhood of middle-class African American families, including architect Wallace Rayfield; Secretary of State Condoleezza Rice; Freeman A. Hrabowski III, president of the University of Maryland, Baltimore County; Birmingham mayor William Bell; former Birmingham Mayor Larry Langford; Birmingham city councillor Carole Smitherman; and Pulitzer Prize-winning journalist Harold Jackson.

[2][3] In June 1993, Titusville residents took the Birmingham city government to court in an attempt to block completion by Browning-Ferris Industries (BFI) of a garbage transfer station in their community.

[4][5][6] This action succeeded in halting the project and was widely celebrated as a grassroots victory over environmental racism.

[4][6] As of 2005[update] the city and county governments agreed to jointly purchase the former Trinity Steel Industries property in Titusville for redevelopment.