Toksook Bay (TOOK-sook or TUCK-sook)[3] is a city[4][5] and village on Nelson Island in Bethel Census Area, Alaska.

[7][8] Almost the entire population are members of the Alaska Native Nunakauyarmiut ("People of Nunakauyaq"), who rely on fishing and other subsistence activities.

The community was chosen as the site of first enumeration of the 2020 U.S. census, due to the remoteness of the Alaskan Bush and the necessity of collecting census data early from remote sites.

The racial makeup of the city was 2.44% White, 94.36% Native American, and 3.20% from two or more races.

Of all households 10.4% were made up of individuals, and 0.9% had someone living alone who was 65 years of age or older.