Tolazamide is an oral blood glucose lowering drug used for people with Type 2 diabetes.

It is part of the sulfonylurea family (ATC A10BB).

para-Toluenesulfonamide is converted to its carbamate with ethyl chloroformate in the presence of a base.

Heating that intermediate with 1-amino-azepane leads to the displacement of the ethoxy group and the formation of tolazemide:[1] Azepane proper would lead to [13078-23-4].

This drug article relating to the gastrointestinal system is a stub.