Tolerable daily intake

[2] TDI is generally written as a value of exposure (e.g. in milligrams) per kilogram (kg) body weight.

[2][4] Because the confounding factors (safety factors) may vary depending on the quality of data and the type of adverse effect, TDI values are not good estimates of the harmfulness of chemicals, and must be considered administrative tools to set allowable limits for chemicals, rather than scientific measures.

The World Health Organization (WHO) has introduced a TDI for melamine as 0.2 milligrams (mg)/kg body weight (b.w.)

[5] Similarly the established TDI range for dioxin according to WHO is 1-4 picograms toxic equivalency/kg body weight as of 1998.

840 micrograms/litre (drinking water)[8] The United States Food and Drug Administration has used TDI for substances such as melamine, which is currently set at 0.063 mg/kg b.w./day.