The tomb was originally built for the brothers Lyson and Kallikles, sons of Aristophanes, around 250 BC and it continued to be used by their descendants for around a century, going out of use around time of Roman conquest.
The walls are painted with pilasters, decked with garlands, support an architrave with guttae.
The most noted paintings from the tomb are the depictions of weapons and armour in the semicircular areas above the doorways on the rear and front walls, which presumably emphasise Lyson and Kallikles' position as members of the Macedonian military aristocracy.
The rear wall depicts a Macedonian shield with the Vergina Sun surrounded by a wreath.
Garlands with ribbons are painted above the niches, as well as the names of the dead, starting with Lyson and Kallikles, and continuing with their descendants for four generations.