The Toronto Central Prison Chapel is an 1877 former Roman Catholic prison chapel, located in Toronto, Ontario, Canada.

The building is the last remaining building of the Toronto Central Prison complex which was located south of King Street and west of Strachan Avenue in Toronto.

The other remaining portion of the prison is a wall of the prison's paint shop on the east side of the Liberty Storage Warehouse.

Its most recent use was as part of the Inglis factory complex that was situated in the area.

In 2011, the prison chapel was slated to become the next location of the Miller Tavern restaurant chain, but the building remains vacant.