In 1414, the condottiero Cabrino Fondulo led Emperor Sigismund of the Holy Roman Empire on a visit to the local castle, accompanied by the three contenders for the papacy, Gregory XII, Benedict XIII and John XXIII.

In 1525, Antonio Maria Picenardi succeeded in acquiring the local castle in its entirety, which was sacked again in 1648 by troops of the Duchy of Modena, which, allied with the French, headed its armies against Spanish-occupied Cremona.

Galeazzo Picenardi was captain of Cremona's urban militia during this same period, which is why his castle was further sacked in 1648 by Agostino da Piadena, a local bandit.

With the Picenardi obtaining the title of marquis in 1714, the complete renovation of the castle began, which would aim to transform the entire complex into a modern villa di delizia.

Also present were the fathers of the monastery of San Salvatore, whose property, however, was forfeited by the Picenardi with the suppression of religious orders in the late 18th century.