Upon the death of Iztacmixcoatzin in 1233 or 1239, Tozcuecuextli took command and shortly after, at the suggestion of Huitziltzin, he emigrated to the Sierra de Guadalupe to exploit the forest and the andesite deposits, near the shore of Lake Texcoco, south of Ecatepec.

, across the lagoon in canoes they transport material more efficiently and continually do work for Azcapotzalco and its dependent towns, without forgetting to do the same with the lordship of Tenayocan.

Marital alliances were also established, which in the long run would give rise to the last Colhua lineage and the second Mexica (the first ws Xaltocamecatl).

Pantitlán also exploits the Sierra de Guadalupe, so at a certain point their interests lead them to war against Huixachtitlan, the final battle taking place near Tecpayocan, the Mexitin win but Tecpatzin dies.

Also shortly after Huitziltzin died, Tozcuecuextli ordered that his remains be transformed into tlaquimilolli (sacred wrapping) and they gave him the name Huitzilopochtli.