As a senior, he recorded 60 tackles and five interceptions as a defensive back, while catching 34 passes for 500 yards and four touchdowns as a wide receiver.

He started the first six games of the season at free safety before moving to cornerback for the final eight contests after the emergence of LaRon Landry.

In 2004, Daniels and fellow senior Corey Webster combined to form one top cornerback tandems in the nation.

[1] At LSU, Daniels was recruited by and played for Nick Saban, who was in his first season as head coach of the Dolphins in 2005.

Along with Ronnie Brown and Channing Crowder, it marked the first time since 1996 that three or more Dolphins rookies started a minimum of 10 games.

Daniels recorded 61 (47 solo) tackles on the year, a figure that ranked fifth on the team and second among defensive backs behind only Lance Schulters' 77.

His first career interception came in the opening of the season when he picked off a Jake Plummer pass in the fourth quarter of a 34–10 win over the Denver Broncos.

His lone fumble recovery came after linebacker Channing Crowder forced the ball from then-Atlanta Falcons fullback Justin Griffith.

In 2006, an ankle injury caused Daniels to miss the entire preseason as well as the first four games of the regular season.

His lone interception came against the Tennessee Titans on September 24, as he picked off a Kerry Collins pass at the Dolphins’ 31 with less than two minutes remaining in the game to preserve a 13–10 win.

On August 20, 2008, the Cleveland Browns acquired Daniels from the Dolphins in exchange for a seventh-round pick in the 2009 NFL draft.