The major treponeme species of human pathogens is Treponema pallidum, whose subspecies are responsible for diseases such as syphilis, bejel, and yaws.

[3] Treponema succinifaciens has been found in the gut microbiome of traditional rural human populations.

[4] The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN)[5] and National Center for Biotechnology Information (NCBI).

Avitreponema avistercoris" Gilroy et al. 2021 T. pedis T. denticola T. putidum T. medium "T. vincentii" (Blanchard 1906) Brumpt 1922 ex Smibert 1984 T. pallidum (Schaudinn & Hoffmann 1905) Schaudinn 1905 [incl.

Treponema paraluiscuniculi (Jacobsthal 1920) Smibert 1974] T. phagedenis "Ca.