[2] The street is named after the Battle of Tres de Abril, an uprising led by Leon Kilat that happened on April 3, 1898 as part of the Philippine Revolution against the Spaniards.

It then becomes a two-way lane and passes through the Taboan Public Market[5] in Barangay San Nicolas Proper which is known for its dried fish.

It curves northeast past T. Abella Street and curves northwest leading to the junction of V. Rama Avenue where the National Historical Commission of the Philippines (NHCP) historical marker of the Battle of Tres de Abril is located.

It once again becomes a one-way lane as it passes through the Adventist Hospital – Cebu and Carlock Street until it reaches the junction of N. Bacalso Avenue.

However, it becomes inaccessible heading towards Barangay Labangon as it becomes a dedicated one-way lane for vehicles coming from A. Lopez and Katipunan streets, and from the other end of Tres de Abril Street where it finally reverts into a two-way lane.