In the early 1930s, the Sisters of The Holy Family of Nazareth came to Tyler, Texas, from the Sacred Heart Province in Chicago to open Mother Frances Hospital.

The hospital was named in honor of Frances Siedliska, the founder of the Sisters of the Holy Family of Nazareth.

[1] The hospital opened on March 18, 1937 – one day ahead of schedule – to provide care for victims of the New London School explosion.

[4] In July 2017, Magnolia Health Systems - Physicians of East Texas (MHS) became a part of Christus Trinity Mother Frances.

1 hospital in Texas for Patient Safety in Overall Hospital and Surgical Care by CareChex (2016); National Benchmarks for Success award winner by Soluticient 2006; winner of the 2007 Texas Health Care Quality Improvement Award; designated as a Blue Cross and Blue Shield Distinction Center+ for Cardiac Care, Bariatric Surgery, Spine Surgery and Knee and Hip Replacement Services; National Research Corporation Consumer Choice winner; and listed among the top five percent in the nation for patient satisfaction by Press Ganey, Inc.[7][8]