Tupiniquins Ecological Station (Portuguese: Estação Ecológica dos Tupiniquins) is a coastal marine ecological station on the coast of São Paulo State, Brazil.

The Tupiniquins Ecological Station is a coastal marine area of 1,728 hectares (4,270 acres) that was created on 21 July 1986.

[1] It is in the municipalities of Cananéia, Itanhaém and Peruíbe in São Paulo State.

[2] The unit includes the following islands and islets:[3] The Ecological Station is a "strict nature reserve" under IUCN protected area category Ia.

Vegetation is from the Atlantic Forest biome with plants typical of salt marshes, sandy ridges, plains and continental beaches.