The station is located in a shopping plaza at the intersection of Jamboree Road and Edinger Avenue.

OCTA buses and City of Irvine's iShuttle also services the station during peak commute hours.

Amtrak's Pacific Surfliner passes through the station at 90 mph (140 km/h) and does not stop in Tustin.

Tustin station is served by 26 Metrolink Orange County Line trains (13 in each direction) each weekday, evenly spaced throughout the day.

Weekend service consists of 4 trains (2 in each direction) on both Saturday and Sunday, heading towards Orange County in the morning and towards the Inland Empire in the evening.