Located east of the Chisholm Trail, Tuttle was developed as a farming and ranching community.

[4] The right-of-way for the St. Louis and San Francisco Railway came from the tribal allotment of Frances Schrock, a Choctaw.

[5] According to the United States Census Bureau, the city has a total area of 29.2 square miles (76 km2), all land.

Nearby Braum's Dairy, the largest farm in the area, is located just outside the city's limits and has a market presence spanning several states.

The Tigers have won 82 state championships in their history as recognized by the Oklahoma Secondary Schools Athletic Association.

The following is a list of the sports in which the school won the state championship: [6] Tuttle has been featured in an Independent Lens series documenting bullying.

Nicknamed "Tigernado", it quickly became a popular hashtag on the social media platform Twitter after reports were made that tigers had escaped the facility.