Tuxcacuesco is a town and municipality, in Jalisco in central-western Mexico.

[2] Tuxcacuesco is home to "Tuxca Corona", a factory started by the Corona family which produces a 100% pure distilled agave liquor.

Tuxcacuesco was a separate state prior to the Spanish incursion.

[3] Novelist Juan Rulfo was born in the town of Apulco in the northeast part of the municipality in 1917.

This article about a location in the Mexican state of Jalisco is a stub.