The Twisleton-Wykeham-Fiennes family (/ˈwɪkəm ˈfaɪnz/) are the descendants of the 16th Baron Saye and Sele who was born Frederick Benjamin Twisleton and adopted the surname Twisleton-Wykeham-Fiennes in 1849 by Act of Parliament.
He was the grandson of Thomas Twisleton, 13th Baron Saye and Sele and inherited the barony from his first cousin William Thomas Eardley-Twisleton-Fiennes in 1847.
The ancestry of the family includes James Fiennes, 1st Baron Saye and Sele (c. 1395–1450) and his father William de Fiennes.
The inheritance included Broughton Castle which became the home of the Barons Saye and Sele, after Thomas Wykeham's granddaughter married William Fiennes, 2nd Baron Saye and Sele.
[1] The Twisleton-Wykeham-Fiennes family are also descendants of John Twisleton (c. 1614–1682) who married Elizabeth Fiennes, the daughter of James Fiennes, 2nd Viscount Saye and Sele, 9th Baron Saye and Sele.