After the bridge ends, the highway makes a loop to the east around a parking structure on Pete Rose and Mehring ways, concurrent with US 52.

The route continues north, passing the west side of the Duke Energy Convention Center, Cathedral Basilica of St. Peter in Chains, and Romanesque Cincinnati City Hall.

The route then follows Colerain Avenue, ascending through the Mount Airy Forest from an elevation of 490 to 930 feet (150 to 280 m) in two miles (3.2 km), passing the Cincinnati Water Tanks on North Bend Road.

A herringbone brick intersection of Chestnut Street and Patterson Avenue is at the southeast corner of Oxford at US 27.

This final section passes to the west of the Oxford Walmart and within a mile (1.6 km) of the Butler County highpoint before reaching College Corner.