The route turns north onto Main Street, passing through downtown Helper.

After curving to the northwest and again to the west, the route ends at a diamond interchange (exit 232) on US-6/US-191.

is a short highway that loops around the town of Price, Utah, beginning and ending at US-6/US-191 in a span of three miles (4.8 km).

runs for approximately 4.7 miles (7.6 km) through Hastings, Nebraska, north of mainline US 6.

followed along Ridge Road, the former alignment of US 6 before the route was moved to the Borman Expressway which also carried Interstate 80 (I-80) and I-94 and half of US 41 through the cities and towns of Northwest Indiana.

The route began in Lansing, Illinois, and heads east across the state line into Munster, Indiana, and traveled through Highland, Griffith, the southern part of Gary, and Hobart (where the road was marked as 37th Avenue).

is an east–west alternate route of US 6 located in Greater Cleveland, traveling 7.30 miles (11.75 km).

Nearly all of its seven-mile (11 km) span follows Detroit Avenue's alignment through Lakewood and Cleveland, which also carried US 20 Alt.

exists to provide a route for truck traffic, as commercial vehicles are prohibited on Clifton Boulevard.

In 1989, a freeway bypass for US 6 was completed on the south side of the Allegheny River, while the original routing plus a connecting bridge were designated as a business loop.

The route was signed in 2000, as a wider (but still two-lane) bypass was constructed along the Susquehanna River to avoid the narrow old alignment.

The route begins as a four-lane undivided highway, featuring a variety of businesses but avoiding the centers of suburbs like Dickson City and Blakely.

It then becomes a two-lane route and skirts north of the narrow suburban finger by traveling through Archbald Pothole State Park and Pennsylvania forestry land.

The route serves as a bypass of the Long Mountain and Palisades Parkways, which are restricted to passenger cars only.

From there, it heads south on NY 403 and US 9 to rejoin US 6 and US 202 at the traffic circle north of Peekskill.

This bypass is an important route for commercial vehicles which cannot traverse Bear Mountain Bridge Road, though they are permitted to do so.

This newer section ends as it merges with Route 101, once the Rhode Island and Connecticut Turnpike, and now called Hartford Pike.

The Rhode Island and Connecticut Turnpike continued to the Olneyville section of Providence, where it is known as Hartford Avenue.

The route begins at US 6 and I-295 in Johnston and follows Hartford Avenue 2.50 miles (4.02 km) through the city.

US 6A continues into Providence, traveling 1.20 miles (1.93 km) along Hartford Avenue to its terminus at US 6.

At the eastern terminus of Route 25, US 6 eastbound once crossed the Cape Cod Canal via the Bourne Bridge then followed Sandwich Road along the south side of the canal to the Sagamore Bridge where it joined the Mid-Cape Highway on its way to Provincetown.