USCGC McLane (WSC-146) is a 125 ft (38 m) United States Coast Guard Active-class patrol boat in commission from 1927 to 1971.

Originally designated WPC, for patrol craft, they were re-designated WSC, for submarine chaser, in February 1942, during World War II.

The "W" appended to the PC (patrol craft) and SC (submarine chaser) designations identified vessels as belonging to the U.S. Coast Guard.

McLane was laid down and launched by American Brown Boveri Electric Corporation, Camden on 22 March 1927.

Throughout World War II, McLane patrolled in the waters of the Territory of Alaska including the Bering Strait.

While on patrol in Dixon Entrance between Alaska and British Columbia on 7 June 1942, McLane received a report of an Imperial Japanese Navy submarine sighted in the area and began a search for it.

The Coast Guard-manned U.S. Navy patrol vessel USS YP-251 and the Royal Canadian Navy minesweeper HMCS Quatsino joined McLane on 9 July 1942, and the three ships began a search for the submarine in Dixon Entrance southeast of Annette Island in Southeast Alaska.

McLane then dropped two depth charges, after which the vessels reported that oil, bubbles, and what appeared to be rock wool (used to deaden sounds in submarines) rose to the surface.