It forms part of the international border between the Vaupés department of Colombia and the Amazonas state of Brazil.

In 1847 an explorer saw a rapid which hurled its waves 12 or 15 metres (40 or 50 ft) in the air, "as if great subaqueous explosions were taking place.

"[3] The river continues eastwards through the Alto Rio Negro Indigenous Territory until it flows into the Rio Negro at São Joaquim, Amazonas.

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