This example of underdominance is stable because any shift in equilibrium would result in selection for the rare allele due to increased resource abundance.
[7] An example of stable underdominance can be found in the African butterfly species Pseudacraea eurytus, which utilizes Batesian mimicry to escape predation.
[8] Models of stable underdominance have shown potential in driving the introduction of refractory genes into pest populations that are responsible for the spread of infective diseases such as malaria and dengue fever.
[10] The genetic construct in this system employs a dsRNAi knockdown of a C-reactive protein, RpL14, as well as a rescue element (a complete copy of the wild type RpL14 gene).
[10] This system of underdominance allowed manipulation of the population and ultimate fixation of the constructed genotype and has potential applications in a number of settings, including agriculture and the reduction of various pest-carried diseases.