UniVBE (short for Universal VESA BIOS Extensions) is a software driver that allows DOS applications written to the VESA BIOS standard to run on almost any display device from around 1990 thru the mid-2000s.
The primary benefit is increased compatibility and performance with DOS games.
Many DOS games include a version of UNIVBE because VESA issues were so widespread.
[1] The software started out as The Universal VESA TSR (UNIVESA), written by Kendall Bennett.
Version 6.5 introduced the ability to use Scitech Display Doctor as wrapper video driver.
SciTech Display Doctor 7.1 marked the final release of SDD, which was available on OS/2, among other operating systems.