In the same year Unipol founded a 50-50 joint venture company Quadrifoglio Vita with Banca Agricola Mantovana.

In December 2000 Unipol purchased 51% shares of BNL Vita, a joint venture with Banca Nazionale del Lavoro from Assicurazioni Generali.

In December 2003 Unipol subscribed to the capital increases of Reti Bancarie, a sub-holding company of Banca Popolare Italiana for €173.4 million.

In early 2006 Unipol's takeover bid of Banca Nazionale del Lavoro was rejected by the Bank of Italy.

[6] After the failed takeover bid [7] Unipol saw its CEO Giovanni Consorte resign in the midst of the bancopoli scandal.

In September 2023, Unipol acquired a 10.2% share of Banca Popolare di Sondrio, thus lifting its stake at 19.7 % of the capital of the bank.