Based in Charlottesville, the Health System also operates satellite locations throughout Virginia, in Albemarle, Amherst, Augusta, Campbell, Fluvanna, Louisa, Nelson, and Orange counties.

[1] In 1995, the maternity ward of the University Medical Center mixed up two newborn babies and sent them home with wrong parents.

[7] Local African American activists, including hospital employees such as Randolph Lewis White, worked with the NAACP to advocate both for desegregated wards and better labor conditions for the hospital's African American staff members.

[8] White and others lobbied state and local officials, and eventually threatened a hospital worker's strike, and then a lawsuit, eventually succeeding in having black patients fully integrated into the previously all-white wards.

[10] In August 2013, with a change in the leadership structure, Dr. Richard Patrick Shannon joined the University of Virginia as the Executive Vice President for Health Affairs.

[16] The West Complex was built as a series of separate buildings from 1901 to 1960, with major construction occurring in the 1930s and 1960s.

At over 200,000 sq ft and seven floors, there are 12 operating rooms in this building and a clinical trials wing.

[21] The hospital provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout the region.

[28] On June 30, 1995, the University Medical Center accidentally interchanged two newborns in its maternity ward causing them to be sent home with wrong parents.

This was not discovered until the summer of 1998 when DNA paternity test was ordered when one of the child's parents were going through a divorce.

[34] Several UVA Medical Center departments are ranked among the top 50 in the nation by U.S. News & World Report.

[39] On March 30, 2009, the UVA medical center was named as one of the top 100 hospitals in America for 2008 by the Thomson Reuters.

In 2010, Dr. Platts-Mills was elected as a Fellow of The Royal Society,[42] the first allergist to be named to this select group.