Upatoi Creek is a 35.5-mile-long (57.1 km)[1] river in western Georgia, just outside Columbus.

The stream continues to the west and southwest through the northern margin of Fort Moore.

The stream continues to the southwest forming the boundary between Muscogee and Chattahoochee counties.

[4] The confluence with the Chattahoochee River is at the Georgia-Alabama border and the western boundary of Fort Moore[5] at 32°22′41″N 84°58′14″W / 32.37806°N 84.97056°W / 32.37806; -84.97056 and an elevation of 177 feet.

[2] Upatoi is a name derived from the Muskogean language meaning either "sheet-like covering" or "bullfrog".