[5] The protein encoded by the VANGL2 gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea.

The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets.

This protein is also involved in the development of the neural plate.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 1 is a stub.