Three oak coffins were uncovered from graves in the Bronze Age mound Guldhøj in Holt near Vamdrup in 1891, and are now on display at the National Museum (Nationalmuseet).

After the Second War of Schleswig in 1864, where Denmark lost Southern Jutland to Germany until 1920, Vamdrup became a border town, where the railway station had important function as a border railway station.

In connection with the industrialisation in the 1950s and 1960s Vamdrup flourished again with many new companies.

Danish Air Transport has its head office in the town.

This article about a location in the Region of Southern Denmark is a stub.