Van Zylsrus is a settlement in John Taolo Gaetsewe District Municipality in the Northern Cape province of South Africa.

The settlement was founded by 6 Trekboer families in 1832, led by the former Heemrad of Calvinia, Petrus van Zyl.

[citation needed] Between 1971 and 2001 it was the location of a Ballistic Missile Battery of the SADF, colocated with an Infantry Company plus a Heavy Mortar Platoon, an Armoured Squadron less one troop, and an advance Radar and Signals Squadron of the SAAF.

The settlement also had its own Commando platoon of 21 Riflemen reinforced by the local SAP helicopter flight and Askari detachment.

This Northern Cape location article is a stub.