Vance is a town in Orangeburg County, South Carolina, United States.

[5] According to the United States Census Bureau, the town has a total area of 0.5 square mile (1.3 km2), all land.

There were 71 housing units at an average density of 141.4 per square mile (54.6/km2).

22.4% of all households were made up of individuals, and 11.9% had someone living alone who was 65 years of age or older.

About 29.8% of families and 38.5% of the population were below the poverty line, including 60.5% of those under the age of eighteen and 25.9% of those 65 or over.