[1] Vasicine has been compared to theophylline both in vitro and in vivo.

[2] It has also been studied in combination with the related alkaloid vasicinone.

Both the alkaloids in combination (1:1) showed pronounced bronchodilatory activity in vivo and in vitro.

[3] Vasicine has a cardiac–depressant effect, while vasicinone is a weak cardiac stimulant; the effect can be normalized by combining the alkaloids.

[3][4] Vasicine is reported to have a uterine stimulant effect.