Her parents were María Eugenia Calderón, a school teacher, and Raúl Magario, a member of Montoneros and the organization's financial administrator.

[1][2] She spent most of her childhood in San Isidro and Ramos Mejía, but after the 1976 coup d'état, her family was forced into exile in Mexico, where she lived for eight years.

[3] The family returned to Argentina in 1984, after the fall of the last military dictatorship, and Raúl Magario was imprisoned; he was released in 1989 following a pardon issued by president Carlos Menem.

[10] She was the first Citizen's Unity candidate for the La Matanza city council at the 2017 legislative election; the candidacy was unsuccessfully denounced as "testimonial" before the provincial Electoral Tribunal.

[11] Ahead of the 2019 general election, Magario was chosen as Axel Kicillof's running mate in the Frente de Todos list for the governorship of Buenos Aires.