Vermilacinia reptilioderma is a rare fruticose lichen found on the Vizcaíno Peninsula and Cedros Island of Baja California.

The thallus is generally divided into slender whip-like cylindrical branches, usually numbering less than 20 that arise from a holdfast.

Lichen substances are triterpenes referred to as T1 and T2, known only from several other species in the subgenus Vermilacinia in the central region of Baja California.

The triterpenes T1 and T2 correspond to their Rf values on thin-layer chromatography plates and were determined by mass spectrometry to have a formula of C30H50O2 (T1) and C30H50OO (T2).

[1] Vermilacinia reptilioderma is similar to V. cedrosensis, with which it often occurs, but differs by its thicker persistent rugose cortex, 45–75 μm thick.