It runs south and east from an intersection with VT 110 in Chelsea to the New Hampshire border in Thetford.

The highway takes a turn to the south towards the town of West Fairlee, where it intersects the western terminus of Route 244.

It continues southward until crossing into the town of Thetford, where it begins to turn back to the east.

Route 113 briefly overlaps US-5 (for about 30 yards), before turning east to cross the river.

Route 113 ends at the bridge crossing, continuing as East Thetford Road in Lyme, New Hampshire, an unnumbered local road which intersects with NH-10 approximately 1 mile (1.6 km) to the east.