Victor E. Velculescu (born August 16, 1970) is a Professor of Oncology and Co-Director of Cancer Biology at Johns Hopkins University School of Medicine.

degree, a Ph.D. in human genetics and molecular biology, and postdoctoral studies at the Johns Hopkins School of Medicine where he remains on the faculty.

These studies led Velculescu to coin the term transcriptome in a 1997 paper to describe the comprehensive gene expression patterns that could now be analyzed.

[9] This approach provided the underlying methodology for next-generation sequencing analyses to detect chromosomal abnormalities in human cancer as well as in prenatal genetic testing.

[21] Using this approach, his laboratory performed the first whole-genome analysis detecting chromosomal alterations in the blood of cancer patients.