Known as Peppers Ferry Road, the state highway runs 10.32 miles (16.61 km) from U.S. Route 11 (US 11) in Fairlawn east to US 460 in Christiansburg.

SR 114 begins at an intersection with US 11 (Lee Highway) in Fairlawn, a community in Pulaski County across the New River from the city of Radford.

The state highway heads east as a five-lane road with a center left-turn lane through a commercial area.

East of the commercial area, SR 114 becomes a four-lane divided highway for a short distance before the westbound direction veers onto the eastbound carriageway.

[1][3] SR 114 continues east as a two-lane road on a single carriageway that passes through farmland to the south of Price Mountain on its way to the town of Christiansburg.

[1][3] Samuel Pepper established a ferry crossing during the 1770s which opened a transportation route during the late colonial and early national periods linking the resources of the west with the population centers in the east.

[13] Also in July 1932, a new piece was created replacing CR 113 running north from VA 10 (now Bonsack Road near US 221/US 460) less than a mile to the Botetourt County line.

[12] VA 114 maintained its Fairlawn to Belmont path unchanged for over 50 years until it was extended east to an interchange on the new US 460 bypass.