The state highway heads southeast as two-lane undivided Great Bridge Boulevard.

SR 190 crosses over Interstate 64 (I-64) (Hampton Roads Beltway) and receives an exit ramp from I-64 heading east; this ramp is used to connect that direction of I-64 with U.S. Route 17 (US 17) (Dominion Boulevard), which the state highway intersects a short distance to the southeast.

Full access to the freeway is provided by heading north on SR 168 Business.

SR 190 has a grade crossing of the Chesapeake and Albemarle Railroad just south of its intersection with Greenbrier Parkway and Butts Station Road.

The state highway enters the city of Virginia Beach north of Volvo Parkway and becomes four lanes at Centerville Turnpike.