Known as Jolliff Road, the state highway runs 3.13 miles (5.04 km) from U.S. Route 13 (US 13), US 58, US 460, and US 460 Alternate north to SR 337 within the independent city of Chesapeake.

SR 191 begins at a four-way intersection with US 13, US 58, US 460, and US 460 Alternate in the Bower's Hill area of the city of Chesapeake.

The south leg of the intersection is also Military Highway, which US 13 and US 460 follow toward Norfolk and Virginia Beach.

The north leg of the intersection is SR 191, which immediately turns west and crosses over I-664 with no access.

The state highway crosses Goose Creek, a tributary of the Western Branch Elizabeth River, and gradually curves north.