WUFO (1080 kHz) is a commercial AM radio station licensed to Amherst, New York, and serving the Buffalo metropolitan area.

The roots of today's WUFO can actually be traced back to 1925, with the founding of WPDQ in Kenmore, New York, a Buffalo suburb.

In 1946, Thaddeus Podbielniak and Edwin R. Sanders (d/b/a Western New York Broadcasting Company) applied to the FCC to construct a 1,000-watt AM radio station on the 1080 allocation in Kenmore.

For the first decade or so of its existence, WXRA was a little-noticed full-service radio station offering a wide variety of music and local news.

In April, McLendon changed the call sign to WYSL (for "Whistle") and dropped the Top 40 format in favor of Beautiful Music.

Toward the end of 1961, however, McLendon moved the WYSL call letters and easy listening format to the 1400 spot on the AM dial (formerly WBNY).

However, Gordon McLendon retained control of the FM station after selling off 1080 to Dynamic and moving the intellectual property of WYSL and its beautiful music format to 1400.

McLendon sold the 1080 frequency to Leonard Walk, who owned a group of Black formatted stations (such as WAMO Pittsburgh and WILD Boston).

Since the callsign was unavailable, the owner instead chose the WUFO call sign and named the station "WU-FO in Buffalo".

WUFO's new format began on November 2, 1962 with famed Cleveland Disc Jockey Eddie O'Jay as the first on the air.

Some include Frankie Crocker, Gary Byrd, Herb Hamlett, Jerry Bledsoe, Thelka McCall and her son Dwayne Dancer Donovan, Don Allen, Jerry Young (Youngblood), Don Mullins, Sunny Jim Kelsey, Mansfield Manns Jr, III., Al Brisbane, Jimmy Lyons, H.F. Stone, Chucky T, Al Parker, Gary Lanier, Kelly Carson, Darcel Howell, Mouzon, David Wilson, Byron Pitts, Mark Vann, "The Discotizer" Keith Pollard and Jheri-Lynn.

In 2013, WUFO 1080 was purchased by Vision Multi Media Group co-owned by Sheila L. Brown and Buffalo City Council Member Darius Pridgen.

[9] WUFO simulcasts on FM translator W243DX, with its transmitter located atop One Seneca Tower in the southern area of Downtown Buffalo.