The station airs classic hits (R&B, pop, and rock music from the mid-1950s through the early-1990s) as well as talk programming.

WWUS covers the lower and middle Keys, and reaches the coast of Cuba near Havana.

Originally, US-1 Radio had its signal on 93.5 FM and broadcast with much lower power.

In August 2013, Gamma Broadcasting, LLC reached a deal to sell its Florida Keys stations (including WWUS) to Florida Keys Media, LLC (a company controlled by Robert H.

In July 2024 the station was sold to Fiorini Keys Media, LLC WWUS was honored with the 2018 National Association of Broadcasters Macaroni Award for small market radio station of the year.