1st EIC voyage (1779–1781): Captain Burnet Abercromby sailed from Portsmouth on 16 June 1779, bound for Madras and Bengal.

[1] 2nd EIC voyage (1783–1784): Captain Henry Churchill sailed from Portsmouth on 10 March 1783, bound for St Helena, Bencoolen, and China.

Homeward bound, Walpole crossed the Second Bar on 25 February 1784, reached St Helena on 14 June, and arrived at the Downs on 21 September.

[1] 3rd EIC voyage (1786–1788): Captain Churchill sailed from the Downs on 4 March 1786, bound for Madras, Bengal, and China.

Homeward bound, she crossed the Second Bar on 19 January 1788, reached St Helena on 6 April, and arrived at the Downs on 24 June.

Homeward bound, she crossed the Second Bar on 7 January 1790, reached St Helena on 31 March, and arrived at the Downs on 31 May.

Homeward bound, she crossed the Second Bar on 19 December, reached St Helena on 7 March 1793, and arrived at the Downs on 16 June.

[1] 6th EIC voyage (1794–1795): Captain Thomas Butler acquired a letter of marque on 28 April 1794.

Homeward bound, she crossed the Second Bar on 27 March, reached Malacca on 26 April and St Helena on 24 August.