A number of Xe-100 small modular reactors designed by X-energy are planned to be installed for nuclear electric power production near the Columbia Generating Station in Washington by the 2030s.

It would be X-energy's second power plant after one in Texas due to be finished by 2030.

[3] In late October, 2024, Amazon.com announced it would fund construction of four X-Energy reactors at Hanford.

[4] The site is opposed by environmental groups including Columbia River Keeper,[5] and the Oregon Conservancy Foundation who oppose new small modular reactors in general.

[6] Columbia River Keeper states that Confederated Tribes of the Umatilla Indian Reservation opposed X-energy's application for a Department of Energy license to operate at the Hanford Site.