“Bob” Enders Jr., FACHE, served as interim President & CEO in 2016, Janie Jaberg, RN, FACHE, served as President & CEO from 2016 to 2020,[5] and Jessie L. Tucker III, Ph.D., FACHE, became the corporation and hospital President & CEO in 2020.

[6][7] In September 2021, Moody's revised the hospital's outlook from negative to stable.

[8] The hospital was recognized as a best maternity care hospital in 2022 [9] and in 2023, UNC Health Wayne earned its highest patient safety and quality ratings in history with a Leapfrog Hospital Safety Grade of "A" and a CMS Star quality rating of 4 out of 5.

[10][11][12] The hospital also earned first ever certifications and accreditations in stroke, total hip and knee replacement, chest pain as well as platinum chest pain/MI care awards and high performance ratings for heart failure, kidney failure, stroke and COPD in 2022 and 2023.

[13][14][15] UNC Health Wayne became a Vizient/AACN Nurse Residency Program site in 2023[16] and was recognized as a top 12% and largest hospital in Eastern North Carolina with the highest consistent quality and patient safety ratings (4-stars and 6 consecutive A grades).