Written by frontman Danny Elfman, it is the theme song to the Weird Science film and television series.

It was released on the film's soundtrack, as well as Oingo Boingo's fifth studio album, Dead Man's Party (1985), in a longer mix.

Elfman claimed to have "heard the whole thing in [his] head" by the time he ran home to his studio to record his demo.

[4] The music video for "Weird Science" features the band performing in an abstract laboratory.

The video appeared in a number of different edits when broadcast, some featuring clips from the John Hughes film and other versions without.