Directed by Leigh Silverman, Lisa Kron and Jayne Houdyshell repeated their roles from the Off-Broadway production.

"[5][6] The play was performed by the Huntington Theatre Company at the Boston University Theater in March 2007, with Kron and Mary Pat Gleason as her mother,[7] and at the Oregon Shakespeare Festival in their 2010 season, running February to June 2010.

The cast starred Natalie Casey as Lisa Kron and Sarah Miles as her mother, with direction by Eve Leigh.

"[9] Kron focuses on her family "medical history and the Lansing, Michigan neighborhood where she grew up to knit together issues of health and illness both in the individual (her chronically unwell mother) and in a community.

'"[5] Ben Brantley, in his review for The New York Times, wrote "What makes 'Well' much more than a clever, deconstructed theatrical riff is the way it keeps surprising itself with glimpses of an emotional depth, both murky and luminous, that goes beyond any tidy narrative.

"[6] Elyse Sommer, in her review for CurtainUp, wrote: "This being a serio-comedy, the final mother-daughter confrontation ends on a satisfying note.