Were Babo (Amharic: ወረ ባቦ) is one of the woredas in the Amhara Region of Ethiopia.

This woreda is named for one of the "Houses" or subgroups of the Wollo Oromo that used to govern the area and is still located there.

The administrative center of Were Babu is Bistima; other towns include Ejersa, Arabati and Bokeksa.

The western part of Were Babo lies in the Ethiopian highlands, with the eastern part stretching down to the lowlands of the Afar Region; elevations range from 700 meters above sea level where the Mille leaves the woreda to 2700 meters at its southernmost point.

The majority of the inhabitants were Muslim, with 97.88% reporting that as their religion, while 2.01% of the population said they practiced Ethiopian Orthodox Christianity.