Wesseln is a village with a long history in the northern part of the town of Bad Salzdetfurth in Lower Saxony, Germany.

In a document written in 1215, Henricus sacerdote de Westene, the priest of Wesseln, was mentioned as a witness in a trial.

Wesseln had a small gothic chapel on the right bank of the Lamme where the priest from Detfurth held regular services.

A church was built on the left bank of the Lamme in 1853–55, and the old chapel was used as a stable and barn until it burnt down in 1905.

The extraction of potash salt at a mine in Salzdetfurth, which started in 1896, and the inauguration of the Lamme Valley Railway in 1900 promoted the economic growth and industrial development of the village.