Nantmeal was named by Welsh immigrants from the village of Nantmel in Radnorshire, now part of Powys.

The incorrect belief that it means 'Honey Brook' is based on a confusion between the personal name 'Mael', and the Welsh word 'mêl', 'honey'.

Pennsylvania Route 23 follows Ridge Road along an east-west alignment across the northern corner of the township.

Pennsylvania Route 82 follows North Manor Road along a north-south alignment through the middle of the township.

Pennsylvania Route 282 follows Creek Road east from PA 82 across the southeastern portion of the township.

Pennsylvania Route 345 follows Bulltown Road northeastward from PA 82 in the northeastern portion of the township.

Finally, Pennsylvania Route 401 follows Conestoga Road along an east-west alignment across the northern corner of the township just south of PA 23.