The three-story building with its main entrance facing Gasmer Street housed the administrative offices, classrooms, a cafeteria, an auditorium, library and a gym.

The curriculum included the academic courses — math, science, English and foreign language; the fine arts — music and art, speech, drama, journalism, home economics; the commercial subjects—typing, business machines, and business law; the industrial arts—mechanical drawing—architectural drawing, woodshop and metal shop; drivers education, physical education and the National Defense Cadet Corps.

The school set up the Oceanography/Living Resource Center to provide oceanography education and biological material for the district's science classes.

The suspect escaped detection and left the campus before administrators realized that a sexual assault had happened.

[6] Ronald Walker pleaded guilty and received 45 years of prison for this and other sexual assault crimes.

A tan or gold 1990s Mercury Cougar used as a getaway car for the shooters was discovered in Stafford on November 30.

[13] A 2007 Johns Hopkins University/Associated Press study referred to Westbury as a "dropout factory" where at least 40% of the entering freshman class does not make it to their senior year.

[14] During that year 41% of high-school-age children zoned to Westbury chose to attend a different Houston ISD school.

[20] Area residents believed that HISD wanted to acquire two more apartment complexes to further expand Westbury,[17] and HISD officials told area residents that they planned to acquire the Westbury Manor Apartments.

[24][25] In April 2015 an HISD spokesperson stated that the district was investigating an incident where a substitute teacher was asked to pass all of his/her students with grades of 80 or above.

[29] Areas zoned to Westbury High include:[30] Many neighborhoods in southwest Houston, including almost all of Westbury,[31] Post Oak Manor, Marilyn Estates,[citation needed] Willowbend,[32] most of Willow Meadows,[33] Glenshire, Parkwest,[citation needed] Maplewood South,[34] about half of the Westwood subdivision,[35] and parts of Brays Oaks (Fondren Southwest),[2] as well as the Harris County portion of the city of Missouri City.

[36] In 1970 the Westwood subdivision, along with some other White communities, was rezoned from Westbury to Madison High School because of a court ruling.

[39][40] In April 2014 the HISD school board decided to rename remaining sports team names of Confederate and Native American mascots due to cultural insensitivity.

[40] According to an article in the Houston Chronicle, the dress code was intended to prevent "gang-affiliated colors" from being a presence in the school.